Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762056 | 0.87 | LMNA (0.50) | TDP1MAOAMAOBALDH1A1ERN1 | |
| SCHEMBL6142827 | 0.86 | TDP1 (0.48) | TDP1ALDH1A1SOS1CHEK2TRIM24 | |
| SCHEMBL8549679 | 0.85 | TDP1 (0.52) | TDP1ALDH1A1CHEK2TRIM24TYR | |
| SCHEMBL25333237 | 0.84 | TDP1 (0.56) | TDP1ALDH1A1CHEK2LMNACYP1A2 | |
| SCHEMBL18957581 | 0.82 | MAOA (0.46) | TDP1MAOAMAOBALDH1A1TRIM24 | |
| SCHEMBL24512757 | 0.82 | TDP1 (0.44) | TDP1MAOAMAOBALDH1A1SOS1 | |
| SCHEMBL24512582 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1SOS1TRIM24TYR | |
| SCHEMBL3694921 | 0.82 | MERTK (0.45) | TDP1CHEK2LMNAMEN1KMT2A | |
| SCHEMBL15096320 | 0.81 | TDP1 (0.47) | TDP1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL5175967 | 0.80 | SOS1 (0.44) | TDP1MAOAMAOBALDH1A1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263911-A | Substituted [1,2,4] triazole and imidazole compounds | BASF SE | 2016-01-20 | — | — | CN | disclosed |
| US-20150351401-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| EP-2935225-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | BASF SE (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095655-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| EP-2746260-A1 | Substituted [1,2,4]triazole and imidazole compounds | BASF SE (DE) | 2014-06-25 | — | — | EP | disclosed |
| CN-102432566-B | 2-(4-phenoxyphenyl)oxirane and preparation method and application thereof | UNIV HUNAN | 2013-09-04 | — | — | CN | disclosed |
| CN-102432566-A | 2- (4-phenoxyphenyl) oxirane and preparation method and application thereof | UNIV HUNAN | 2012-05-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150351401-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | CYP1B1, CYP4B1, COX4I1 | TDP1 1077/4885MAOA 224/4885MAOB 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.