Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472196 | 0.80 | TRPM8 (0.53) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL10608486 | 0.79 | KMT2A (0.71) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL13536797 | 0.79 | SMN1; SMN2 (0.50) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL1619155 | 0.78 | MAPT (0.48) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL3868528 | 0.78 | PTGS2 (0.55) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL2795176 | 0.78 | POLB (0.58) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL4842036 | 0.78 | SMN1; SMN2 (0.63) | KMT2AMEN1RAB9AHTTMAPK1 | |
| SCHEMBL839926 | 0.78 | MEN1 (0.69) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL23280 | 0.77 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL18894356 | 0.77 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |