Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442243 | 0.94 | TRPV1 (0.49) | TRPV1FKBP1AASAH1LMNATSHR | |
| SCHEMBL8522522 | 0.90 | MEN1 (0.47) | TRPV1FKBP1AASAH1LMNAALDH1A1 | |
| SCHEMBL8521285 | 0.90 | MEN1 (0.47) | TRPV1FKBP1AASAH1LMNAALDH1A1 | |
| SCHEMBL8521282 | 0.90 | MEN1 (0.47) | TRPV1FKBP1AASAH1LMNAALDH1A1 | |
| SCHEMBL8442958 | 0.89 | MAPT (0.47) | TRPV1FKBP1AASAH1LMNAKMT2A | |
| SCHEMBL8440327 | 0.89 | TRPV1 (0.44) | TRPV1FKBP1ALMNAGAAGFER | |
| SCHEMBL8590402 | 0.87 | ALDH1A1 (0.43) | TRPV1FKBP1AKDM4ELMNATSHR | |
| SCHEMBL8438725 | 0.86 | TRPV1 (0.41) | TRPV1FKBP1AASAH1LMNASMN1; SMN2 | |
| SCHEMBL8554153 | 0.85 | HPGD (0.46) | FKBP1ANAMPTASAH1LMNAALDH1A1 | |
| SCHEMBL8443146 | 0.84 | LMNA (0.41) | TRPV1FKBP1ANAMPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865429-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-09-23 | — | — | EP | claimed |
| WO-1997021676-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-19 | — | — | WO | claimed |