Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.37 |
| ▸ | BPTF | Q12830 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544525 | 0.83 | SMN1; SMN2 (0.40) | MTORMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8544138 | 0.79 | BPTF (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL4292263 | 0.75 | NPC1 (0.50) | MTORMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL4282771 | 0.75 | KAT2B (0.33) | MTORMAPTKAT2BBRD9BPTF | |
| SCHEMBL8545709 | 0.74 | BRD9 (0.42) | MTORMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL17912364 | 0.72 | KAT2B (0.56) | MAPTALDH1A1RAB9AKAT2BBRD9 | |
| SCHEMBL21383748 | 0.71 | — | — | |
| SCHEMBL14844575 | 0.71 | NPBWR1 (0.43) | MTORMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL4292123 | 0.70 | MAPT (0.36) | MAPTALDH1A1BRD9BRD4MEN1 | |
| SCHEMBL23318253 | 0.68 | KAT2B (0.43) | MTORMAPTNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717734-B1 | PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5763439-A | POTENTIATION | ISHIHARA SANGYO KAISHA LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0717734-A1 | PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007264-A1 | PYRIDAZINONE DERIVATIVES OR THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, AND ANTI-SHOCK AGENTS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |