Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828382 | 0.81 | CYP1A2 (0.36) | CYP1A2POLB | |
| SCHEMBL8550007 | 0.76 | CTSA (0.33) | FLT4CYP1A2CYP3A4CYP2C19ROCK2 | |
| SCHEMBL2476178 | 0.72 | SLC6A2 (0.34) | NPC1CYP3A4ADORA2AADORA1 | |
| SCHEMBL8543574 | 0.69 | CASP3 (0.39) | NPC1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL9028689 | 0.68 | SCN9A (0.37) | ROCK2 | |
| SCHEMBL8017632 | 0.67 | HSPA5 (0.55) | NPC1CYP1A2CYP3A4CYP2C19ADORA2A | |
| SCHEMBL16672689 | 0.67 | ESR1 (0.41) | POLB | |
| SCHEMBL8745918 | 0.67 | HRH1 (0.35) | CYP3A4POLB | |
| SCHEMBL15243101 | 0.66 | POLB (0.46) | POLBLPAR1 | |
| SCHEMBL12578615 | 0.65 | SLC6A2 (0.35) | CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308826-A | Pre- and postemergence herbicides; controlling weeds, particularly broad leaf plants and grasses | ZENECA LIMITED (GB) | 1994-05-03 | — | — | US | claimed |
| EP-0695292-B1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5585327-A | PRE- AND POST-EMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| WO-1994024106-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-5308826-A | Pre- and postemergence herbicides; controlling weeds, particularly broad leaf plants and grasses | ZENECA LIMITED (GB) | 1994-05-03 | — | — | US | disclosed |