Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550024 | 0.93 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL28343702 | 0.85 | MAPT (0.45) | ALDH1A1TSHRDAOHDAC3HDAC4 | |
| SCHEMBL29224872 | 0.83 | HDAC3 (0.45) | ALDH1A1TSHRDAOHDAC3HDAC4 | |
| SCHEMBL8549207 | 0.83 | PKM (0.46) | ALDH1A1DAOHDAC3HDAC4HDAC1 | |
| SCHEMBL16753170 | 0.82 | GSK3B (0.49) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL5068414 | 0.80 | HDAC3 (0.65) | ALDH1A1TSHRDAOHDAC3HDAC4 | |
| SCHEMBL8549910 | 0.77 | LMNA (0.53) | ALDH1A1TSHRDAOHDAC3HDAC4 | |
| SCHEMBL27537636 | 0.77 | DAO (0.44) | ALDH1A1TSHRDAOHDAC3HDAC4 | |
| SCHEMBL8545143 | 0.77 | DAO (0.48) | ALDH1A1DAOPKMLIG1LMNA | |
| SCHEMBL29224870 | 0.76 | ALDH1A1 (0.60) | ALDH1A1TSHRDAOHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719774-B1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0719774-A1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5310940-A | Sulfiding, cyclization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5221749-A | Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5093504-A | PRODUCTION OF THIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS, TETRAHYDROTHIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS AND DIBENZOXAZOLYLTHIOPHENES | SUMITOMO SEIKA CHEMICALS, CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |