Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192462 | 0.87 | NT5E (0.43) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL4429332 | 0.84 | HSP90AA1 (0.53) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL30329198 | 0.84 | HSP90AA1 (0.53) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL29383511 | 0.79 | NT5E (0.38) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL16634931 | 0.79 | KDM4E (0.40) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL28664997 | 0.79 | NT5E (0.38) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL31039307 | 0.79 | NT5E (0.38) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL3101735 | 0.79 | NT5E (0.38) | NT5EKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL2395464 | 0.77 | ALDH1A1 (0.43) | NT5EKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22321641 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991669-B | Fluorine-containing tag for protein cysteine residue modification and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2025-04-01 | — | — | CN | disclosed |
| CN-115991669-A | Fluorine-containing tag for protein cysteine residue modification and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2023-04-21 | — | — | CN | disclosed |
| EP-2676963-B1 | NOVEL COMPOUND, NOVEL LIGAND, NOVEL TRANSITION METAL COMPLEXES, AND CATALYSTS CONSISTING OF NOVEL TRANSITION METAL COMPLEXES | UNIV OKAYAMA NAT UNIV CORP (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| US-8779133-B2 | Compound, novel ligand, novel transition metal complex, and catalyst including novel transition metal complex | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| US-5719169-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| EP-0640593-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0640593-A1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024680-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | NT5E 4255/4885KDM4E 306/4885ALDH1A1 121/4885 |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | NT5E 4255/4885KDM4E 306/4885ALDH1A1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.