Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547551 | 0.88 | — | — | |
| SCHEMBL8549667 | 0.84 | MAOB (0.53) | MAOB | |
| SCHEMBL8551507 | 0.83 | PPARA (0.42) | KMT2ASMN1; SMN2MAOBALOX5FFAR1 | |
| SCHEMBL8551123 | 0.83 | PARP15 (0.47) | KMT2ASMN1; SMN2MAOBALOX5 | |
| SCHEMBL8545547 | 0.82 | PPARA (0.47) | MAOBFFAR1 | |
| SCHEMBL8550604 | 0.82 | CYP2D6 (0.50) | — | |
| SCHEMBL8545384 | 0.81 | PPARA (0.50) | KMT2ASMN1; SMN2MAOBMEN1 | |
| SCHEMBL28087440 | 0.80 | MME (0.60) | KMT2ASMN1; SMN2MAOBNR4A2MME | |
| SCHEMBL7900754 | 0.78 | KMT2A (0.57) | KMT2ASMN1; SMN2MAOBNR4A2FFAR1 | |
| SCHEMBL7900762 | 0.78 | KMT2A (0.57) | KMT2ASMN1; SMN2MAOBNR4A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |