Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549667 | 0.84 | MAOB (0.53) | — | |
| SCHEMBL8551507 | 0.83 | PPARA (0.42) | — | |
| SCHEMBL8551123 | 0.83 | PARP15 (0.47) | — | |
| SCHEMBL8545547 | 0.82 | PPARA (0.47) | — | |
| SCHEMBL8550070 | 0.82 | KMT2A (0.50) | — | |
| SCHEMBL7908798 | 0.82 | CYP2D6 (0.56) | CYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL7908799 | 0.82 | CYP2D6 (0.56) | CYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL8545384 | 0.81 | PPARA (0.50) | — | |
| SCHEMBL8550601 | 0.81 | CYP2D6 (0.53) | CYP2D6SLC6A2SLC6A4NOS2 | |
| SCHEMBL8550287 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |