Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545547 | 0.89 | PPARA (0.47) | PPARAPPARGPPARDALDH1A1MAOB | |
| SCHEMBL8549667 | 0.88 | MAOB (0.53) | PPARAPPARGPPARDMAOBMAOA | |
| SCHEMBL8551123 | 0.87 | PARP15 (0.47) | PPARAPPARGPPARDKMT2ASMN1; SMN2 | |
| SCHEMBL7907396 | 0.85 | NMT1 (0.46) | NMT1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL7907397 | 0.85 | NMT1 (0.46) | NMT1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL8551507 | 0.82 | PPARA (0.42) | PPARAPPARGPPARDKMT2ASMN1; SMN2 | |
| SCHEMBL8545380 | 0.81 | NMT1 (0.44) | NMT1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL8550604 | 0.81 | CYP2D6 (0.50) | — | |
| SCHEMBL8550070 | 0.81 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL8549924 | 0.80 | GPR132 (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |