Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.41 |
| ▸ | PRKCB | P05771 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCH | P24723 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787958 | 0.78 | CHRM2 (0.44) | MEN1KMT2ACHRM2CHRM3CHRM4 | |
| SCHEMBL23600324 | 0.78 | CHRM2 (0.44) | MEN1KMT2ACHRM2CHRM3CHRM4 | |
| SCHEMBL8552616 | 0.78 | BCHE (0.48) | MEN1KMT2APRKCGPRKCBPRKCA | |
| SCHEMBL25698496 | 0.73 | PRKCG (0.53) | MEN1KMT2APRKCGPRKCBPRKCA | |
| SCHEMBL19157371 | 0.73 | GBA1 (0.50) | GBA1REN | |
| SCHEMBL25698185 | 0.72 | SLC18A3 (0.52) | MEN1KMT2APRKCGPRKCBPRKCA | |
| SCHEMBL8550092 | 0.72 | PTPRF (0.45) | HPGDMAPTPTPRFPTPN2PTPN1 | |
| SCHEMBL23478117 | 0.71 | CHRM2 (0.45) | RAB9ACHRM2CHRM3CHRM4CHRM1 | |
| SCHEMBL27324278 | 0.71 | CHRM2 (0.47) | MEN1KMT2ACHRM2CHRM3CHRM4 | |
| SCHEMBL6119861 | 0.71 | CHRM2 (0.47) | MEN1KMT2ACHRM2CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |