Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550095 | 0.78 | MEN1 (0.46) | BCHEMEN1KMT2ARAB9AMAPT | |
| SCHEMBL23600324 | 0.74 | CHRM2 (0.44) | MEN1KMT2A | |
| SCHEMBL27787958 | 0.74 | CHRM2 (0.44) | MEN1KMT2A | |
| SCHEMBL2505463 | 0.74 | MEN1 (0.46) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8552611 | 0.74 | MEN1 (0.47) | BCHEMEN1KMT2AMAPTPOLB | |
| SCHEMBL8549295 | 0.71 | MEN1 (0.64) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL14256172 | 0.70 | CHRM2 (0.49) | BCHERAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL6119861 | 0.70 | CHRM2 (0.47) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8686857 | 0.70 | MEN1 (0.62) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL16897810 | 0.69 | REN (0.49) | BCHERAB9AMAPTALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |