Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551253 | 0.99 | PDE2A (0.33) | PDE2ACNR2CNR1KDM4ETDP1 | |
| SCHEMBL8550106 | 0.88 | PDE2A (0.35) | PDE2A | |
| SCHEMBL8553961 | 0.88 | TDP1 (0.34) | TDP1 | |
| SCHEMBL8548822 | 0.87 | TDP1 (0.35) | TDP1 | |
| SCHEMBL8549196 | 0.87 | PDE2A (0.35) | PDE2A | |
| SCHEMBL8552056 | 0.87 | LMNA (0.31) | — | |
| SCHEMBL8551648 | 0.86 | LMNA (0.31) | — | |
| SCHEMBL8553039 | 0.86 | SMN1; SMN2 (0.35) | PDE2AKDM4E | |
| SCHEMBL8552341 | 0.85 | PDE2A (0.33) | PDE2ACNR2CNR1KDM4ETDP1 | |
| SCHEMBL8551255 | 0.82 | S1PR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |