Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550783 | 0.91 | USP2 (0.34) | CNR2CACNA1DHTR2BHTR6PTGDR2 | |
| SCHEMBL8552697 | 0.87 | TDP1 (0.38) | TDP1 | |
| SCHEMBL8553301 | 0.87 | PDE2A (0.36) | PDE2A | |
| SCHEMBL8550150 | 0.86 | LMNA (0.34) | — | |
| SCHEMBL8551253 | 0.86 | PDE2A (0.33) | PDE2ACNR2CNR1KDM4ETDP1 | |
| SCHEMBL8550130 | 0.85 | PDE2A (0.33) | PDE2ACNR2CNR1KDM4ETDP1 | |
| SCHEMBL8552377 | 0.85 | SMN1; SMN2 (0.37) | PDE2AKDM4E | |
| SCHEMBL8552344 | 0.83 | S1PR1 (0.30) | CNR2 | |
| SCHEMBL8550785 | 0.81 | PPARG (0.36) | CNR2PPARDRXRACACNA1DHTR2B | |
| SCHEMBL8667814 | 0.80 | HTR2B (0.34) | CNR2KDM4ETDP1CACNA1DHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |