SCHEMBL8550192

SCHEMBL8550192

C=CC(=O)OCC(CN1C(=O)C2CCCCC2C1=O)OC(=O)C=C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
ALDH1A1 P00352 6/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
RAB9A P51151 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8549183 0.84 HTT (0.41) HTTTSHRTP53ALDH1A1LMNA
SCHEMBL8554011 0.82 TSHR (0.31) TSHR
SCHEMBL23581828 0.80 HTT (0.39) HTTTSHRTP53ALDH1A1LMNA
SCHEMBL15730302 0.77 TSHR (0.41) TSHRTP53ALDH1A1
SCHEMBL206200 0.75 HTT (0.44) HTTTSHRTP53ALDH1A1LMNA
SCHEMBL14370793 0.75 TSHR (0.44) TSHRTP53ALDH1A1
SCHEMBL8552467 0.73 TSHR (0.46) HTTTSHRTP53ALDH1A1RAB9A
SCHEMBL700993 0.72 TSHR (0.59) TSHRTP53ALDH1A1
SCHEMBL8551817 0.71 ALDH1A1 (0.51) HTTTSHRTP53ALDH1A1RAB9A
SCHEMBL782188 0.71 SMN1; SMN2 (0.36) HTTTSHRALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US claimed
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed