SCHEMBL8554011

SCHEMBL8554011

C=CC(=O)OCC(CN1C(=O)C2C=CCCC2C1=O)OC(=O)C=C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8550192 0.82 HTT (0.39) TSHR
SCHEMBL8550908 0.81 TSHR (0.34) TSHR
Acrylic Acid SCHEMBL29047109 0.78 THRB (0.34) TSHR
SCHEMBL8550911 0.73 CYP3A4 (0.30) TSHR
SCHEMBL15730302 0.70 TSHR (0.41) TSHR
SCHEMBL3847282 0.70 ALDH1A1 (0.44)
SCHEMBL14370793 0.68 TSHR (0.44) TSHR
SCHEMBL10967255 0.68 ALDH1A1 (0.31)
SCHEMBL8549183 0.67 HTT (0.41) TSHR
SCHEMBL11818302 0.67 SMN1; SMN2 (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US claimed
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed