Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068448 | 0.77 | TDP1 (0.59) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL26547090 | 0.76 | TDP1 (0.47) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL8665006 | 0.73 | TDP1 (0.47) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL8550600 | 0.73 | ALDH1A1 (0.51) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL21396290 | 0.73 | TDP1 (0.54) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL7402152 | 0.72 | TDP1 (0.46) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL17965803 | 0.72 | TDP1 (0.61) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL17965761 | 0.72 | TDP1 (0.61) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL7323211 | 0.72 | TDP1 (0.53) | RAB9AKMT2ANPC1TDP1SLC6A2 | |
| SCHEMBL26390430 | 0.72 | TDP1 (0.53) | RAB9AKMT2ANPC1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |