Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27006674 | 0.82 | TSHR (0.50) | ALDH1A1L3MBTL1TSHRCYP3A4KMT2A | |
| SCHEMBL2705753 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL29353285 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL27584631 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL9692230 | 0.76 | MAPT (0.48) | ALDH1A1TDP1L3MBTL1TSHRKMT2A | |
| SCHEMBL26188531 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL18717240 | 0.74 | TDP1 (0.59) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL4881052 | 0.73 | MEN1 (0.46) | ALDH1A1TDP1TSHRKMT2AMAPT | |
| SCHEMBL8550289 | 0.73 | RAB9A (0.47) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL50441 | 0.73 | ALDH1A1 (0.89) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |