Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8548633 | 0.99 | PLG (0.41) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8553715 | 0.90 | NR1H2 (0.38) | PLGKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8547668 | 0.89 | PLAU (0.37) | PLGKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8552083 | 0.81 | MEN1 (0.34) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8374823 | 0.80 | PLAU (0.47) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| SCHEMBL8518199 | 0.80 | PLG (0.45) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8549377 | 0.80 | PLG (0.55) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8548609 | 0.79 | PLAU (0.44) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8547382 | 0.79 | PLAU (0.46) | PLGKMT2AMEN1ALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL8547928 | 0.79 | PLG (0.44) | PLGKMT2AMEN1ALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |