Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 4/20 | 0.32 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553715 | 0.91 | NR1H2 (0.38) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8546417 | 0.81 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8550323 | 0.81 | PLG (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8554002 | 0.81 | PLAU (0.44) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8547668 | 0.80 | PLAU (0.37) | MEN1KMT2AALDH1A1HTTMAPT | |
| Hydrochloric Acid SCHEMBL8548633 | 0.80 | PLG (0.41) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8552079 | 0.77 | SMN1; SMN2 (0.34) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8551154 | 0.73 | CA9 (0.33) | MAPTNR1H2NR1H3SMN1; SMN2LMNA | |
| SCHEMBL8548298 | 0.70 | PLAU (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8548156 | 0.70 | SMN1; SMN2 (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |