Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SETDB1 | Q15047 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | PCNA | P12004 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28786869 | 0.87 | KDM4E (0.46) | ALDH1A1MAPTKDM4EF13A1MTNR1A | |
| SCHEMBL861177 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL853998 | 0.84 | BDKRB1 (0.44) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL855591 | 0.84 | SETDB1 (0.40) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL855405 | 0.82 | SETDB1 (0.41) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL2697301 | 0.78 | SETDB1 (0.38) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL24185372 | 0.77 | NOS2 (0.47) | KMT2AALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL28945087 | 0.76 | KDM4E (0.44) | ALDH1A1MAPTKDM4EF13A1MTNR1A | |
| SCHEMBL27825579 | 0.74 | KDM4E (0.43) | ALDH1A1MAPTKDM4EF13A1MTNR1A | |
| SCHEMBL27804931 | 0.74 | KDM4E (0.43) | ALDH1A1MAPTKDM4EF13A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2242739-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2014-11-12 | — | — | EP | disclosed |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-8410141-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8304371-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| CN-102438984-A | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG | 2012-05-02 | — | — | CN | disclosed |
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | BAY CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2242739-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003690-A1 | INSECTICIDAL ARYLPYRROLINES | DDT, ACHE, CYP1A2 | KMT2A 775/4885ALDH1A1 127/4885MAPT 4128/4885 |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | KMT2A 635/4885ALDH1A1 121/4885MAPT 4047/4885 |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | KMT2A 635/4885ALDH1A1 121/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.