Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855405 | 0.95 | SETDB1 (0.41) | SETDB1CD274RECQLALDH1A1MAPT | |
| SCHEMBL861177 | 0.90 | KMT2A (0.40) | SETDB1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL2697304 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL855039 | 0.78 | KMT2A (0.38) | SETDB1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL853998 | 0.78 | BDKRB1 (0.44) | SETDB1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL28945087 | 0.78 | KDM4E (0.44) | ALDH1A1MAPTKDM4E | |
| SCHEMBL855591 | 0.78 | SETDB1 (0.40) | SETDB1CD274ALDH1A1MAPTKMT2A | |
| SCHEMBL11159589 | 0.72 | MIF (0.34) | — | |
| SCHEMBL24185372 | 0.72 | NOS2 (0.47) | ALDH1A1MAPTKMT2AKDM4EHDAC1 | |
| SCHEMBL28786869 | 0.68 | KDM4E (0.46) | ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410141-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | SETDB1 4416/4885CD274 4331/4885RECQL 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.