Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554481 | 0.85 | ALDH1A1 (0.36) | KDM1ACHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7518110 | 0.84 | ALDH1A1 (0.35) | KDM1ACHRNB2CHRNA4 | |
| SCHEMBL8551464 | 0.81 | — | — | |
| SCHEMBL8553260 | 0.81 | — | — | |
| SCHEMBL8671400 | 0.81 | — | — | |
| SCHEMBL8554778 | 0.80 | CHRNA3 (0.35) | — | |
| SCHEMBL8551060 | 0.80 | MEN1 (0.33) | IRAK4CHRNB2CHRNA4 | |
| SCHEMBL8550718 | 0.80 | MEN1 (0.33) | IRAK4CHRNB2CHRNA4 | |
| SCHEMBL8508196 | 0.79 | — | — | |
| SCHEMBL8616694 | 0.79 | CHRNB2 (0.32) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |