Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550439 | 1.00 | ITGB3 (0.38) | ITGB3ITGA2BFLT3MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL8621613 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BFLT3MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL8621616 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BFLT3MAPK11MAPK14 | |
| Hydrochloric Acid SCHEMBL8553242 | 0.83 | MAPK11 (0.36) | MAPK11MAPK14HPGDSCFTRPDGFRB | |
| SCHEMBL8554046 | 0.81 | LMNA (0.42) | ITGB3ITGA2BHPGDS | |
| SCHEMBL8554049 | 0.81 | LMNA (0.42) | ITGB3ITGA2BHPGDS | |
| Hydrochloric Acid SCHEMBL8549999 | 0.80 | LMNA (0.41) | ITGB3ITGA2BHPGDS | |
| Hydrochloric Acid SCHEMBL8555002 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8553733 | 0.72 | SMYD3 (0.48) | ITGB3ITGA2BFLT3CFTRSMYD3 | |
| Bromide SCHEMBL8549638 | 0.72 | SMYD3 (0.35) | ITGB3ITGA2BFLT3HPGDSSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |