Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187602 | 0.94 | NR1H4 (0.64) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL14405820 | 0.91 | GAA (0.59) | ALDH1A1KDM4ETP53MAPTGAA | |
| SCHEMBL8550447 | 0.91 | ABCB1 (0.57) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL7009532 | 0.90 | KMT2A (0.58) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL7370844 | 0.90 | SMN1; SMN2 (0.55) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL3493914 | 0.89 | RAB9A (0.58) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL14518119 | 0.89 | MAPT (0.61) | ALDH1A1KDM4ETP53MAPTL3MBTL1 | |
| SCHEMBL8681578 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETP53MAPT | |
| SCHEMBL7294828 | 0.88 | MAPT (0.73) | ALDH1A1HPGDTP53MAPTL3MBTL1 | |
| SCHEMBL8626583 | 0.87 | ABCB1 (0.54) | ALDH1A1HPGDKDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |