Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290666 | 0.78 | CXCL8 (0.46) | ALDH1A1LMNANPSR1KMT2AHPGD | |
| SCHEMBL31599176 | 0.78 | LMNA (0.88) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8544104 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL1200434 | 0.76 | LMNA (0.68) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4434944 | 0.76 | LMNA (0.75) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3144872 | 0.76 | LMNA (0.65) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31241185 | 0.76 | LMNA (0.65) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31599172 | 0.74 | LMNA (0.72) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9639641 | 0.74 | LMNA (0.72) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7920811 | 0.74 | LMNA (0.64) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |