Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445183 | 0.89 | BCHE (0.54) | DYRK1AELANEKDM4EATMMAPT | |
| SCHEMBL9089933 | 0.89 | BCHE (0.54) | DYRK1AELANEKDM4EATMMAPT | |
| SCHEMBL8548702 | 0.88 | LMNA (0.45) | ELANEKDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7840124 | 0.77 | GABRA1 (0.41) | ELANEKDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL8545879 | 0.76 | GAA (0.47) | ELANEKDM4ETSHRSMN1; SMN2ALOX15 | |
| SCHEMBL29445130 | 0.76 | BCHE (0.58) | DYRK1AKDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL8546738 | 0.76 | BCHE (0.58) | DYRK1AKDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL29445100 | 0.76 | KDM4E (0.58) | DYRK1AKDM4EMAPTTSHRNPC1 | |
| SCHEMBL9090021 | 0.76 | KDM4E (0.58) | DYRK1AKDM4EMAPTTSHRNPC1 | |
| Dimethylamine SCHEMBL8546919 | 0.74 | BCHE (0.51) | DYRK1AKDM4EMAPTHASPINDYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591058-B1 | Ellipticine derivatives with antitumor activity | ADIR (FR) | 1998-06-03 | — | — | EP | disclosed |
| US-5498611-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1996-03-12 | — | — | US | disclosed |
| US-5407940-A | Antitumor agents | ADIR ET COMPAGNIE (FR) | 1995-04-18 | — | — | US | disclosed |
| EP-0591058-A1 | Ellipticine derivatives with antitumor activity | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | disclosed |