Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253053 | 0.78 | ALDH1A3 (0.55) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL1915714 | 0.77 | ALDH1A3 (0.58) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL8192949 | 0.74 | ALDH1A3 (0.55) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL1915741 | 0.73 | ALDH1A3 (0.53) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL607344 | 0.72 | DRD1 (0.88) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL14016002 | 0.72 | ALDH1A3 (0.76) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL384361 | 0.72 | ALDH1A3 (1.00) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL4048430 | 0.72 | ALDH1A3 (0.62) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL14003721 | 0.72 | ALDH1A3 (0.51) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A | |
| SCHEMBL1915454 | 0.72 | ALDH1A3 (0.51) | ALDH1A3DRD1ALDH1A1CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |