Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 6/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541299 | 0.91 | KDM4E (0.56) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24709914 | 0.89 | PTGER4 (0.44) | MEN1KMT2ASIRT1SIRT5SIRT2 | |
| SCHEMBL7740151 | 0.88 | KDM4E (0.59) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL29357392 | 0.88 | SIRT2 (0.49) | SIRT1SIRT5SIRT2SIRT3 | |
| SCHEMBL4727432 | 0.88 | SIRT2 (0.49) | SIRT1SIRT5SIRT2SIRT3 | |
| SCHEMBL4076285 | 0.88 | SIRT2 (0.49) | SIRT1SIRT5SIRT2SIRT3 | |
| SCHEMBL7934318 | 0.86 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10727549 | 0.86 | SIRT2 (0.50) | KDM4EALDH1A1HPGDSIRT1SIRT5 | |
| Hydrochloric Acid SCHEMBL380911 | 0.86 | SIRT2 (0.49) | KDM4EALDH1A1HPGDSIRT1SIRT5 | |
| SCHEMBL1842451 | 0.85 | SIRT2 (0.46) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863883-A1 | ALPHA-(1,3-DICARBONYLENOL ETHER) METHYL KETONES AS CYSTEINE PROTEASE INHIBITORS | PROTOTEK, INC., (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0863883-A4 | — | — | 1998-09-16 | — | — | EP | disclosed |