Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593632 | 1.00 | HTR2B (0.45) | HTR2BHRH3ITGB3ITGA2BADRB3 | |
| SCHEMBL8550693 | 0.90 | HTR2B (0.43) | HTR2BHRH3ITGB3ITGA2BADRB3 | |
| SCHEMBL8590784 | 0.88 | HRH3 (0.40) | HTR2BHRH3ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8355309 | 0.87 | HTR2B (0.47) | HTR2BITGB3ITGA2BF10 | |
| SCHEMBL8551353 | 0.87 | HTR2B (0.42) | HTR2BHRH3ADRB3KCNH2CCR8 | |
| SCHEMBL8589135 | 0.87 | HRH3 (0.44) | HRH3ITGB3ITGA2BADRB3CYP2C9 | |
| SCHEMBL8552884 | 0.87 | HTR2B (0.43) | HTR2BHRH3CCR8POLB | |
| SCHEMBL8351475 | 0.85 | HTR2B (0.45) | HTR2BITGB3ITGA2B | |
| SCHEMBL8644656 | 0.85 | HRH3 (0.39) | HRH3ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8351727 | 0.83 | HTR2B (0.47) | HTR2BHRH3ITGB3ITGA2BADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | claimed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | claimed |