Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552786 | 0.90 | HTR2B (0.45) | HTR2BADRB3HRH3SIGMAR1CCR8 | |
| SCHEMBL8593632 | 0.90 | HTR2B (0.45) | HTR2BADRB3HRH3SIGMAR1CCR8 | |
| SCHEMBL8351621 | 0.88 | HTR2B (0.45) | HTR2BF10ITGB3ITGA2B | |
| SCHEMBL8351689 | 0.86 | HTR2B (0.43) | HTR2BADRB3CCR8F10ITGB3 | |
| SCHEMBL8552905 | 0.85 | SIGMAR1 (0.33) | HTR2BSIGMAR1 | |
| SCHEMBL8551745 | 0.83 | HRH3 (0.36) | HRH3ITGB3ITGA2B | |
| SCHEMBL8551353 | 0.81 | HTR2B (0.42) | HTR2BADRB3HRH3CCR8 | |
| SCHEMBL8552884 | 0.79 | HTR2B (0.43) | HTR2BHRH3CCR8 | |
| SCHEMBL8551028 | 0.79 | HTR2B (0.41) | HTR2BADRB3 | |
| SCHEMBL8590784 | 0.79 | HRH3 (0.40) | HTR2BHRH3SIGMAR1F10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |