Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555012 | 1.00 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| SCHEMBL7816781 | 0.93 | SLC6A2 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| SCHEMBL7414007 | 0.86 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| Hydrochloric Acid SCHEMBL7409243 | 0.85 | CHRNB2 (0.30) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| SCHEMBL8555994 | 0.83 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| SCHEMBL8554469 | 0.80 | IRAK4 (0.40) | — | |
| SCHEMBL8550597 | 0.80 | SLC6A2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8552875 | 0.80 | SLC6A2 (0.33) | CHRNA3 | |
| SCHEMBL8552096 | 0.80 | SLC6A2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA2 | |
| SCHEMBL8554864 | 0.80 | SLC6A2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |