Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7409243 | 0.92 | CHRNB2 (0.30) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7816781 | 0.87 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7408878 | 0.86 | CHRNB2 (0.37) | CHRNB2PDCD1LG2CD274CHRNA4 | |
| SCHEMBL8556820 | 0.86 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8550798 | 0.86 | CHRNB2 (0.37) | CHRNB2PDCD1LG2CD274CHRNA4 | |
| Hydrochloric Acid SCHEMBL7406659 | 0.85 | CHRNB2 (0.36) | CHRNB2PDCD1LG2CD274CHRNA4 | |
| SCHEMBL8552081 | 0.80 | IRAK4 (0.41) | — | |
| SCHEMBL8555012 | 0.80 | CHRNB2 (0.33) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8551114 | 0.80 | CHRNB2 (0.33) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8554864 | 0.80 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | claimed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |