Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469178 | 0.94 | LMNA (0.42) | TSHRMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8554377 | 0.92 | LMNA (0.37) | TSHRMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8603405 | 0.91 | TSHR (0.42) | TSHRMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8602448 | 0.90 | HIF1A (0.39) | TSHRMAPK1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8603746 | 0.89 | LMNA (0.36) | TSHRMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8555228 | 0.89 | LMNA (0.37) | TSHRMAPK1MAPTSMN1; SMN2LMNA | |
| SCHEMBL7465815 | 0.89 | TSHR (0.40) | TSHRMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8602122 | 0.89 | TSHR (0.44) | TSHRMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7471326 | 0.88 | MEN1 (0.39) | TSHRMAPK1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8558097 | 0.88 | KMT2A (0.37) | TSHRMAPTSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |