Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603405 | 0.92 | TSHR (0.42) | TSHRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8604688 | 0.91 | GSK3B (0.40) | TSHRLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7469178 | 0.90 | LMNA (0.42) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8551402 | 0.89 | MEN1 (0.39) | TSHRLMNAMAPK1NPSR1ALDH1A1 | |
| SCHEMBL8551162 | 0.89 | TSHR (0.39) | TSHRLMNAMAPK1USP2ATM | |
| Hydrochloric Acid SCHEMBL8602861 | 0.89 | MEN1 (0.39) | LMNAMAPK1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8554377 | 0.88 | LMNA (0.37) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8558097 | 0.87 | KMT2A (0.37) | TSHRLMNASMN1; SMN2MAPTTP53 | |
| SCHEMBL8602448 | 0.86 | HIF1A (0.39) | TSHRLMNAMAPK1USP2ATM | |
| SCHEMBL8603746 | 0.86 | LMNA (0.36) | TSHRLMNAMAPK1USP2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |