Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469178 | 0.91 | LMNA (0.42) | KMT2ATP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL8603405 | 0.91 | TSHR (0.42) | KMT2AMEN1TP53SMN1; SMN2NPC1 | |
| SCHEMBL8554377 | 0.89 | LMNA (0.37) | KMT2ATP53SMN1; SMN2NPC1LMNA | |
| SCHEMBL8551162 | 0.88 | TSHR (0.39) | KMT2AMEN1TP53SMN1; SMN2GAA | |
| SCHEMBL8604688 | 0.87 | GSK3B (0.40) | KMT2AMEN1TP53SMN1; SMN2LMNA | |
| SCHEMBL7465815 | 0.87 | TSHR (0.40) | TP53SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL7463274 | 0.87 | LMNA (0.37) | KMT2AMEN1TP53SMN1; SMN2NPC1 | |
| SCHEMBL8602448 | 0.87 | HIF1A (0.39) | KMT2ATP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL8555228 | 0.86 | LMNA (0.37) | KMT2AMEN1TP53SMN1; SMN2NPC1 | |
| SCHEMBL7468335 | 0.86 | TP53 (0.35) | KMT2ATP53SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |