Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502727 | 0.91 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2TTRLTA4HHTT | |
| SCHEMBL13857071 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL32670495 | 0.88 | LPAR1 (0.45) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL9502764 | 0.88 | LPAR1 (0.45) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL9502738 | 0.88 | LTA4H (0.55) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL9502686 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MITFMEN1GAA | |
| SCHEMBL32670336 | 0.87 | MAOB (0.50) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL32670407 | 0.87 | MMP14 (0.46) | ALDH1A1SMN1; SMN2MITFST14MEN1 | |
| SCHEMBL32670377 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MITFMEN1GAA | |
| SCHEMBL6159557 | 0.87 | MMP14 (0.46) | ALDH1A1SMN1; SMN2MITFST14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |