Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103803 | 0.87 | PDE10A (0.38) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL8710076 | 0.77 | TP53 (0.41) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL8970101 | 0.73 | MEN1 (0.51) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL84705 | 0.70 | GRM5 (0.46) | MEN1KMT2APABPC1TP53POLB | |
| SCHEMBL27361024 | 0.69 | MEN1 (0.48) | MEN1KMT2APABPC1TP53MAPT | |
| SCHEMBL24999134 | 0.68 | ADORA2A (0.45) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL13749571 | 0.67 | MEN1 (0.46) | MEN1KMT2APABPC1TP53MAPT | |
| SCHEMBL18726784 | 0.66 | TP53 (0.41) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL5317523 | 0.66 | TP53 (0.41) | MEN1KMT2APABPC1TP53PDE10A | |
| SCHEMBL7017923 | 0.66 | TP53 (0.44) | MEN1KMT2APABPC1TP53PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021865-A1 | TRICYCLIC ERYTHROMYCIN DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-05-06 | — | — | WO | claimed |
| CN-1234718-C | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-01-04 | — | — | CN | disclosed |
| CN-1464880-A | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-12-31 | — | — | CN | disclosed |
| WO-1999021865-A1 | TRICYCLIC ERYTHROMYCIN DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-05-06 | — | — | WO | disclosed |