SCHEMBL8551418

SCHEMBL8551418

CCCCCCCCC1Cc2ccc(-c3ncc(-c4ccc(OC(=O)C5CCCO5)cc4)cn3)cc2C1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 6/20 0.37
RAB9A P51151 2/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
NAMPT P43490 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 2/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
FASN P49327 2/20 0.32
LTA4H P09960 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
RARB P10826 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8553550 0.94 MCHR1 (0.37) MCHR1RAB9AHSD17B10LMNAMAPK1
SCHEMBL8555768 0.88 LMNA (0.38) MCHR1RAB9AHSD17B10LMNAMAPK1
SCHEMBL8553936 0.82 KMT2A (0.41) RAB9AMAPK1SMN1; SMN2NPC1RARB
SCHEMBL8553224 0.79 NPC1 (0.45) RAB9AHSD17B10SMN1; SMN2HPGDLTA4H
SCHEMBL8553403 0.77 RAB9A (0.43) RAB9AHSD17B10SMN1; SMN2HPGDNPC1
SCHEMBL8558587 0.76 FYN (0.36) RAB9AHSD17B10SMN1; SMN2HPGDNPC1
SCHEMBL8557226 0.74 MAPT (0.50) RAB9AHSD17B10SMN1; SMN2HPGDNPC1
SCHEMBL8553157 0.74 RAB9A (0.42) RAB9AHSD17B10SMN1; SMN2HPGDNPC1
SCHEMBL8556698 0.74 RAB9A (0.36) RAB9AHSD17B10SMN1; SMN2HPGDNPC1
SCHEMBL8551722 0.73 FYN (0.40) RAB9AHSD17B10SMN1; SMN2HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546338-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1998-02-04 EP disclosed
US-5385692-A Improved response CANON KABUSHIKI KAISHA (JP) 1995-01-31 US disclosed