Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551418 | 0.88 | MCHR1 (0.37) | LMNAMAPK1RAB9AHSD17B10HPGD | |
| SCHEMBL8553550 | 0.87 | MCHR1 (0.37) | LMNAMAPK1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL8554498 | 0.72 | CYP3A4 (0.39) | RAB9AALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL8553936 | 0.70 | KMT2A (0.41) | MAPK1RAB9AALDH1A1NPC1KMT2A | |
| SCHEMBL10342273 | 0.67 | MAPT (0.40) | LMNAMAPK1RAB9AHSD17B10HPGD | |
| SCHEMBL10342275 | 0.67 | MAPT (0.40) | LMNAMAPK1RAB9AHSD17B10HPGD | |
| SCHEMBL10342272 | 0.67 | MAPT (0.40) | LMNAMAPK1RAB9AHSD17B10HPGD | |
| SCHEMBL9395847 | 0.66 | HPGD (0.47) | MAPK1RAB9AALDH1A1HSD17B10HPGD | |
| SCHEMBL8553157 | 0.66 | RAB9A (0.42) | RAB9AALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL8556698 | 0.66 | RAB9A (0.36) | RAB9AALDH1A1HSD17B10HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |