Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8547889 | 0.99 | ENPP3 (0.40) | ENPP3KDM4ETHRBNPSR1GPR174 | |
| SCHEMBL8374822 | 0.79 | NPSR1 (0.39) | ENPP3KDM4ETHRBNPSR1KDR | |
| SCHEMBL8518196 | 0.79 | NPSR1 (0.39) | ENPP3KDM4ETHRBNPSR1KDR | |
| Hydrochloric Acid SCHEMBL8549372 | 0.79 | NPSR1 (0.39) | ENPP3KDM4ETHRBNPSR1KDR | |
| SCHEMBL8551831 | 0.79 | NPSR1 (0.37) | ENPP3KDM4ETHRBNPSR1KDR | |
| Hydrochloric Acid SCHEMBL8547376 | 0.78 | NPSR1 (0.39) | ENPP3KDM4ETHRBNPSR1KDR | |
| Hydrochloric Acid SCHEMBL8547922 | 0.78 | NPSR1 (0.39) | ENPP3KDM4ETHRBNPSR1KDR | |
| Hydrochloric Acid SCHEMBL8548606 | 0.78 | ALDH1A1 (0.42) | ENPP3KDM4ETHRBNPSR1KDR | |
| Hydrochloric Acid SCHEMBL8552862 | 0.78 | NPSR1 (0.37) | ENPP3KDM4ETHRBNPSR1KDR | |
| SCHEMBL8547602 | 0.77 | NPSR1 (0.36) | ENPP3KDM4ETHRBNPSR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |