Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine, 4-(1,3-Dioxalan-2-Yl) SCHEMBL3965171 | 0.72 | ALDH1A1 (0.44) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL8829940 | 0.68 | CYP11B1 (0.31) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL9451016 | 0.67 | MEN1 (0.44) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL4900607 | 0.67 | MEN1 (0.38) | — | |
| Pyridine, 4-(1,3-Dioxalan-2-Yl) SCHEMBL11687893 | 0.67 | ALDH1A1 (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7192970 | 0.64 | CYP2C19 (0.45) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL9518449 | 0.63 | CCNB2 (0.39) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL533185 | 0.63 | MEN1 (0.37) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL366283 | 0.61 | CYP2C19 (0.62) | — | |
| SCHEMBL16503674 | 0.61 | CCNB2 (0.37) | CCNB2CDK1CCNB1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582304-B1 | Methods of producing amino butene derivatives | FUJIREBIO KK (JP) | 1998-04-01 | — | — | EP | claimed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | claimed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | claimed |
| EP-0582304-B1 | Methods of producing amino butene derivatives | FUJIREBIO KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |