Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.66 |
| ▸ | RXRB | P28702 | 11/20 | 0.66 |
| ▸ | RARB | P10826 | 10/20 | 0.66 |
| ▸ | RARG | P13631 | 9/20 | 0.66 |
| ▸ | RXRG | P48443 | 7/20 | 0.66 |
| ▸ | RARA | P10276 | 6/20 | 0.65 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972592 | 1.00 | RXRA (0.66) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL10354287 | 0.84 | CYP3A4 (0.60) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL10354286 | 0.84 | CYP3A4 (0.60) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL846110 | 0.82 | RARB (0.81) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL29827631 | 0.82 | RARB (0.81) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL8556759 | 0.82 | RXRA (0.62) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL7688234 | 0.81 | RARB (0.47) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL8461871 | 0.81 | RARB (0.62) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL7688235 | 0.81 | RARB (0.47) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL8461869 | 0.81 | RARB (0.62) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | claimed |
| EP-0170105-B1 | BENZOIC ACID DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1990-10-17 | — | — | EP | claimed |
| US-5767146-A | Anti-osteopathic composition | HOECHST JAPAN LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5716995-A | TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS | HOECHST JAPAN LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5703128-A | TREATING OSTEOPOROSIS, BONE FRACTURES | HOECHST JAPAN LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5525618-A | ENHANCING OSTEOGENESIS, PREVENTING OSTEOPOROSIS | HOECHST JAPAN LIMITED (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | disclosed |