Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 18/20 | 0.44 |
| ▸ | DRD3 | P35462 | 18/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386505 | 0.84 | OPRD1 (0.38) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL7489657 | 0.81 | OPRM1 (0.48) | DRD2HTR2A | |
| SCHEMBL8550891 | 0.81 | DRD2 (0.47) | DRD2SLC6A4 | |
| SCHEMBL8551776 | 0.76 | DRD2 (0.47) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8703615 | 0.74 | DRD2 (0.53) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8550901 | 0.72 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL8710593 | 0.69 | CHRM4 (0.42) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8551958 | 0.69 | DRD2 (0.57) | DRD2HTR2ADRD3 | |
| SCHEMBL8547950 | 0.69 | DRD2 (0.57) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8551530 | 0.69 | DRD2 (0.54) | DRD2SLC6A4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |