Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605054 | 0.93 | TSHR (0.43) | TSHRMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8554097 | 0.93 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604584 | 0.90 | KDM4E (0.45) | TSHRMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8603793 | 0.87 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604513 | 0.84 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8600794 | 0.83 | TP53 (0.38) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604456 | 0.82 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2TP53GSK3B | |
| SCHEMBL8557139 | 0.82 | TP53 (0.42) | ALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8554618 | 0.81 | KDM4E (0.41) | TSHRMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8600322 | 0.80 | TSHR (0.42) | TSHRTP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |