Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604584 | 0.90 | KDM4E (0.45) | KDM4EFNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8605041 | 0.88 | ALDH1A1 (0.38) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8551402 | 0.88 | MEN1 (0.39) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8602861 | 0.87 | MEN1 (0.39) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8643936 | 0.84 | MAOB (0.43) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7471326 | 0.84 | MEN1 (0.39) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8603793 | 0.84 | ALDH1A1 (0.45) | LMNAALDH1A1TP53SMN1; SMN2SLC5A1 | |
| SCHEMBL8604456 | 0.83 | TSHR (0.45) | KDM4EFNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8604248 | 0.82 | ALDH1A1 (0.38) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8605054 | 0.81 | TSHR (0.43) | ALDH1A1MAPTTP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |