Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 15/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553942 | 0.91 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8551698 | 0.89 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8554476 | 0.87 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2PPARGPTPN1 | |
| SCHEMBL8602443 | 0.84 | HTT (0.51) | TSHRALDH1A1PPARG | |
| SCHEMBL7473022 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8552323 | 0.81 | TSHR (0.41) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8552329 | 0.81 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8555694 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8552185 | 0.80 | PPARG (0.45) | ALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8595934 | 0.80 | TSHR (0.44) | TSHRALDH1A1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |