Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026192 | 0.88 | CYP1A2 (0.49) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL9025896 | 0.87 | CYP2C9 (0.49) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL2992736 | 0.87 | RAB9A (0.74) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL31515434 | 0.87 | CYP2C9 (0.74) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL9027024 | 0.86 | CYP2D6 (0.49) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL9025242 | 0.86 | CYP2C9 (0.70) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL2986625 | 0.86 | RAB9A (0.72) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL5352269 | 0.86 | RAB9A (0.72) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL8500695 | 0.85 | NPC1 (0.71) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 | |
| SCHEMBL2983653 | 0.85 | RAB9A (0.71) | RAB9ACYP2C9NPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |