Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | USP14 | P54578 | 1/20 | 0.47 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023049 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL1546955 | 0.85 | TDP1 (0.58) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL14880649 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL472686 | 0.83 | VCAM1 (0.62) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL17826828 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL16959600 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL17341954 | 0.79 | ALDH5A1 (0.44) | ALDH1A1VCAM1HTTMAPTMEN1 | |
| SCHEMBL22040900 | 0.79 | VCAM1 (0.54) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL30993761 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1CASP3USP14 | |
| SCHEMBL27889233 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103080101-A | Piperidinyl-substituted lactams as GPR119 modulators | ARRAY BIOPHARMA INC | 2013-05-01 | — | — | CN | disclosed |
| EP-0833630-A4 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN INC (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0833630-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | Sugen, Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040110-A1 | NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |