Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670343 | 0.88 | DRD2 (0.39) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8103660 | 0.84 | NOTUM (0.45) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8089666 | 0.84 | DRD2 (0.44) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8668048 | 0.84 | HCRTR1 (0.42) | DRD2DRD3HCRTR1HCRTR2MCHR1 | |
| SCHEMBL6507979 | 0.82 | DRD2 (0.43) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8788747 | 0.81 | CA12 (0.45) | DRD2DRD3KCNH2 | |
| SCHEMBL8670349 | 0.81 | KMT2A (0.33) | DRD2DRD3KCNH2HCRTR1HCRTR2 | |
| SCHEMBL27509910 | 0.78 | DRD2 (0.40) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8554695 | 0.77 | DRD2 (0.50) | DRD2DRD3KCNH2OPRL1NOTUM | |
| SCHEMBL8593553 | 0.77 | OPRL1 (0.42) | DRD2DRD3KCNH2OPRL1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1203599-A | Substitued pyrrolidinone, thiazolidinone or oxazolidinone as herbicides | ZENECA LTD (GB) | 1998-12-30 | — | — | CN | disclosed |
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |